There may be risks to the mother and fetus associated with untreated IDA in pregnancy. The iron released by this drug does pass into human breast milk. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. They can tell you about other medications that may work well for you. Venofer (Iron Sucrose Injection): Uses, Dosage, Side Effects - RxList You may report side effects to the FDA at 1-800-332-1088. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. What is the latest research on the form of cancer Jimmy Carter has? Its because everyones body is different. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. Injectafer contains the active drug ferric carboxymaltose. Call your doctor for instructions if you miss an appointment for your Venofer injection. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Brand-name medications usually cost more than generics. A healthcare provider will give you this injection. The drug helps increase your hemoglobin level back to a value thats within the normal range. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. If these effects continue or worsen, tell your doctor. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Keep all regular medical and laboratory appointments. Learn about the causes, symptoms, diagnosis, and treatment of this. Learn about uses, cost, how it works, and more. It is important to get each dose of this medication as scheduled. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. Other drugs are available that can treat iron deficiency anemia (IDA). Dizziness. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. There are different types of anemia, but IDA is the most common type. This survey is being conducted by the WebMD marketing sciences department. Last updated on Feb 20, 2023. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. fever. Iron infusions are given directly into a vein. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Heres some detail on certain side effects this drug may cause. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. (See also Notes section.). There are currently no generic forms of either drug. Some drugs may have another patient information leaflet. Follow all instructions closely. Side effects from HRT depend on a number of factors: This medication is given by injection into a vein as directed by your doctor. Venofer (iron sucrose) Uses, Dosage, Side Effects, FAQ - MedicinesFAQ The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. Dizziness. * Feraheme has a boxed warning for this side effect. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Medically reviewed by Sanjai Sinha, MD. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. How Long Does An Acid Trip Last? [Doctor-Reviewed Guide] <> What to Know About Iron Infusions for Anemia Treatment - GoodRx This can be very helpful in . In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. During Injectafer treatment, your doctor will likely order blood tests. So we cant say for sure whether the drug is safe to use while youre pregnant. Venofer Intravenous: Uses, Side Effects, Interactions, Pictures - WebMD An iron infusion is a way to increase the body's iron levels quickly. Does Daxxify Work Better Than Botox? I Tried The New Neurotoxin. Check with your pharmacist if you have questions about the best way to throw out drugs. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Theyll likely have you stop taking the pills while youre using Injectafer. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Consult your doctor before breast-feeding. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. This information is not specific medical advice and does not replace information you receive from the healthcare provider. Injectafer and Feraheme are both brand-name drugs. If you have questions about side effects, call your doctor. Follow your doctor's directions carefully. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. The Injectafer dosage your doctor prescribes will depend on your body weight. Venofer may reduce the absorption of iron preparations taken by mouth. Below are examples of these side effects. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. After the infusion, you can drive yourself home and return to your usual activities. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. Change in taste. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Then your body uses that iron to make hemoglobin and RBCs. This medication is given by injection into a vein as directed by your doctor. They can recommend appropriate treatment options. Youll receive doses of either drug by a healthcare professional at a medical facility. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Side effectswill last a very long time if the cause of them is not resolved. Tell your doctor about the allergy and what signs you had. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Cancer patients who have anemia and are taking an ESA. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Side Effects of Venofer (Iron Sucrose Injection), Warnings, Uses - RxList There may be drug take-back programs in your area. Its not known if Injectafer is safe to use during pregnancy. Tell your doctor if you are taking iron supplements or other iron-based oral medications. As with all medications, the cost of Injectafer can vary. Common and Rare Side Effects for Venofer Vial - WebMD But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. For some people, it may be OK to continue taking a multivitamin that contains iron. People with IDA have low blood levels of hemoglobin. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Things to remember when you fill your prescription. Use Venofer as ordered by your doctor. Always review your medical history with the treatingphysician. Pain in your limbs. Someside effectsare temporary or last as long as the person continues takingprescription medicine. In the US - Call your doctor for medical advice about side effects. Dating an Addict in Recovery: What to Expect Many patients with kidney disease cannot get enough iron from food and require injections. Available for Android and iOS devices. MNT is the registered trade mark of Healthline Media. FG Trade/E+ sia Getty Images Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Possibleside effectsareweight gainand suicidal thoughts. One of the most commonly used tests to monitor IDA is the hemoglobin test. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Red Tide in Florida: What You Need to Know | OutCoast.com IQVIA [NSP Audit from MAT November 2013 to November 2018]. Venofer is for use in adults and children at least 2 years old. (Hemoglobin is a protein thats found in your red blood cells.). This test measures the amount of hemoglobin in your blood. Back pain. With slow IV injection, the drug is given as a single, slow injection into your vein. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. These nutrients include iron, vitamin B12, and folate. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. You may report side effects to FDA at 1-800-FDA-1088. This gives a total cumulative dose of 1,500 mg of Injectafer. No, you most likely wont take Injectafer long term. We cancelled my 5th because of the reaction. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Details. Copyright 1996-2023 Cerner Multum, Inc. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. Venofer (iron sucrose) dosing, indications, interactions, adverse Hemoglobin is a protein thats found in your RBCs. % Or your doctor may recommend that you change your eating habits to include more iron in your diet. Theyll do this by checking certain blood tests. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. You may need extra iron because of blood loss during kidney dialysis. Venofer Side Effects: Common, Severe, Long Term - Drugs.com Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Venofer treatment may be repeated if iron deficiency reoccurs. Injectafer infusions are given over a period of at least 15 minutes. Why is the range so wide? taste impairment. Their medical staff can help you set up another time to receive your Injectafer dose. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. This is not a complete list of possible side effects. During pregnancy, this medication should be used only when clearly needed. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or All rights reserved. Your doctor will go over your
Venofer Side Effects. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Its possible to get rid of or reduce the severity ofside effects. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. They have been a god send. With IV infusion, the drug is given as a slow drip into your vein over a period of time. This website is intended for use by US healthcare professionals only. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Its caused by your body not having enough iron, which is needed to make hemoglobin. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. intense abdominal pain. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Injectafer contains the active drug ferric carboxymaltose. Venofer may cause significant hypotension (decreased blood pressure). Should I avoid certain foods while taking Venofer Vial? Most people do not know how long theirside effectswill last until they go through them. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. This information should not be used to decide whether or not to take Venofer or any other medicine. And these two doses need to be separated by at least 7 days. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. cough. It is very important that your doctor check you closely while you are receiving this medicine. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. All rights reserved. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Before using, check this product visually for particles or discoloration. Side Effects of Intravenous Iron | livestrong Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. The drug helps increase your hemoglobin level back to a value thats within the normal range. Precautions. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Do not exceed 1,500 mg of iron per dosing course. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Call your doctor right away if you have serious side effects. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. 1 0 obj The researchers looked to see how well each drug worked to increase peoples hemoglobin level. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes But you kidneys need iron in order to make EPO. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Injectafer isnt a medication that youll take regularly on a schedule. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; But for other people, doing so could lead to having too much iron in their body. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. (Hemoglobin is a protein thats found in red blood cells.). In the second group, some people switched from taking iron by mouth to taking Injectafer. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. These changes could help improve your anemia on a long-term basis. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Here we look at how Injectafer and Feraheme are alike and different. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Together, they can recommend ways to help you manage a body weight thats healthy for you. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Injectafer helps to treat IDA by providing an iron infusion directly into your body. "That's why it's so . In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. But the length of time that this may take varies from person to person. Theyll recommend how to manage your condition. (And Injectafer is used to treat IDA.) Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. It is given into a vein for a period of time. On day three I had a headache and felt heavy/exhausted, which lasted a few days. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. But some people have a delayed allergic reaction to certain drugs. Talk with the doctor. You may also report side effects at https://www.fda.gov/medwatch. How long does iron infusion stay in your system? 4 0 obj WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. I used to get a different type but my . This allows them to manage any side effects that you may have following your dose. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. This may lead to the person needing a higher dose compared to someone who is muchsmaller. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. endobj
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